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Uehara et al., 1995

Reverse transcription was performed using a High Capacity cDNA Reverse Transcription Kit (Applied Biosystems, Thermo Fisher Scientific) with 1,000 ng of RNA following the manufacturer's instructions and using a ProFlex PCR System (Applied Biosystems, Thermo Fisher Scientific) machine

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Chlamydia pneumoniae : An etiologic agent for late-onset dementia

A laboratory synthesizes it for the first time, discovers it seems to have interesting properties, and spends many years studying it in rodents

That idea has enough biologic plausibility to be interesting